*Side Effects of Cytomel – Hypothyroidism: There has long since been a fear of thyroid medications among many people due to the issue of hypothyroidism, which simply refers to the thyroids inability to manufacture adequate amounts of thyroid hormones. The idea is simple, synthetic thyroid mediations are used, they are discontinued and at this stage the body no longer has the ability to make its own as it has become dependent on the exogenous hormones. Many fear they will become fat and uncontrollably so due to the T3 hormone playing such an important role on the metabolism. When it comes to the side effects of Cytomel, without question this one has been blown beyond out of proportion. It would truly take massive high dose long term use to truly cause hypothyroidism in an otherwise healthy adult. The thyroid will start making its own T3 very rapidly after use is discontinued, and at a much stronger rate than say testosterone after natural testosterone has been suppressed. That aside, in order to facilitate a smooth recovery it’s not a bad idea to drop down to a low dose for a week or two before discontinuing use completely. There’s no need to ramp down, simply drop down to a low maintenance dose and then discontinue.