Drostanolone metabolites uses

Like other AAS, drostanolone is an agonist of the androgen receptor (AR). [3] It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity. [3] As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites . [3] While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives. [3] Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . [3]

Not many anabolic drugs give a chiseled and hardened look that Masteron is capable of. This is because of its anti-estrogen properties explained earlier. A lot of body builders say that their muscles feel fuller and tighter with the use of Masteron. The drug extracts water from between the muscles and skin, resulting in the visibility of finer muscle details. It is important to remember that this happens only with a body fat percent that is below 10. Masteron on its own is a very weak anabolic steroid and needs to be used with other stringer ones. But it does serve the dual purpose of “cutting” and countering water and estrogen related side effects caused by the use of other drugs.

Because the ultimate goal of a steroid cycle is to increase strength and muscle size, the associated spike in estrogen which accompanies steroids such as Testosterone is considered undesirable. In order to disassociate the two effects, two classes of drug are used. Medications such as Nolvadex or Clomid target the estrogen receptors. They make it more difficult for the estrogen to exert it’s influence within the body thus allowing the testosterone to act more freely. The second class is aromatase inhibitors such as Femara. They target the aromatase enzyme itself in order to prevent the production of estrogen in the first place. Sometimes, it’s not always clear which option you should go with or even what the differences are between the two. Lets clear that up a little.

Drostanolone metabolites uses

drostanolone metabolites uses


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